Greg Tyrelle
Bioinformatics Territory Specialist
Commercially oriented bioinformatician with a wide range of experience in genomics data analysis. Ranging from small bacterial de novo genome assembly, to full scale whole human genome analysis and interpretation. Working closely with sales, I have a deep understand of how NGS technologies are being employed in markets such as academia, pathology/oncology, pharma, clinical and agribio. I specialize in taking complex bioinformatics analysis workflows, methods and statistical approaches and distilling these to their core concepts to communicate with customers.
Experience
Thermo Fisher
July 2019 - Present
Application Territory Specialist, Bioinformatics
I moved to the Application Territory Specialist team as the group's bioinformatics subject matter expert in 2019. I continue to support early access programs, now with a focus on Reproductive Health and Expanded Carrier Screening. Developing and supporting sequencing appraoches to detecting SARS-CoV-2 on the Genexus instrument has been a major effort since March 2020.
- Developed internal training courses on Bioinformatics for the Field Application Science Team
- Supported early access for the Oncomine Comprehensive assay Plus and Genexus Sequencing instrument
- Supported early access for the Amplsieq SARS-CoV-2 panel with key public health institutes in Europe
- Developed national database inetgration for pathology customers in the Netherlands
- Consulting on custom (White Glove) Ampliseq Panel designs and analysis
Thermo Fisher
October 2014 - June 2019
Field Bioinformatics Scientist (Territory Specialist)
As the Territory Specialist in the Field Bioinformatics team, I manage technical support for key accounts on the Ion Torrent platform, early access technology programs, and escalations. Domains include AgriBio, Oncology Infectious Diseases.
I also act as manager and developer for Professional Services projects on the Ion Torrent Platform. Building accurate Statment of Work documents with clients for projects and definining deliverables.
- Developed automated data anlysis pipelines and backend integration for AgriBio customers
- Bioinformatics support lead in EMEA for Ion Torrent early access technology programs in Oncology
- Consulting on novel Ampliseq application development
Thermo Fisher
2012 - 2014
Senior Field Bioinformatics Scientist
Pre and post sales support for SOLiD and Ion platforms, Professional Services (data analysis) and training.
- Project manager and data analyst for whole human genome population study
- Customer training and optimization of diagnostic gene panels in clinical setting
- Study design and data analysis for key customer exome data platform comparison
Complete Genomics
2011 - 2012
Senior Field Application Scientist
Pre and post sales support for whole human genome data sets, both cancer and germline.
- On-site customer data deliverables training
- Assisted customers to solve rare disease cases with genome sequencing
DNAge B.V.
2009 - 2011
Senior Bioinformatics Scientist
Bioinformatics R&D role in small Dutch startup working aging interventions
- Analyzed microarray data to support orphan drug clinical trial
- Integrated data across different omics technologies to provide key insights into accelerated aging
Phalanx Biotech Group
2006 - 2009
Bioinformatics Manager
Managed a team of bioinformaticians doing R&D on microarray design and annotation:
- Built customized human and mouse microarray annotation pipeline
- Designed and implemented online data delivery service
Education
University of New South Wales
NSW, Australia
2000 - 2004
PhD Bioinformatics
Developed ontologies and software tools for variant calling and annotation for a custom SBE genotyping array.
Technical skills
Statistics
good
NGS resequencing
extensive knowledge
Personalized medicine
extensive knowledge
Python programming
extensive experience
R/Bioconductor
good
NGS Transcriptomics
good
De novo assembly
good
Clinical NGS
good